CLINICAL PHARMACOLOGY
- Overview
- Assessment methods
- Learning objectives
- Contents
- Bibliography
- Teaching methods
- Contacts/Info
A thorough comprehension of the course entails basic knowledge in general pharmacology (imparted during the first year of the Midwifery bachelor degree in the Course of Biomedical Sciences), human physiology (imparted during the first year of the Midwifery bachelor degree in the Course of Genetica Medica e Fisiologia Umana) and general and clinical pathology (imparted during the first year of the Midwifery bachelor degree in the Course of Microbiology, General and Clinical Pathology).
There are no constraining pre-requisites for this course.
Knowledge verification is based on an oral examination concerning the subjects and skills discussed during the frontal lessons. The objective is to verify whether the student has reached the previously described formative objectives and will be pursued by evaluating the degree of knowledge and deepening of the different subjects. In particular, the degree of knowledge and understanding will weigh the 40% of the final vote, the ability to apply the knowledge and skills acquired during the lessons will weigh the 25% of the final vote, the autonomy of judgement will weigh the 25% and the communicative skills will weigh the 10%. Evaluation will be expressed in 30/30, and a minimal score of 18/30 will be necessary to pass. The score obtained in the course of Pharmacology will be added to those obtained in the other four disciplines of the Integrated Course of Clinical Pathology and Anaesthesiology, and the final vote will consists of the median value. In case that, even in just one of the five disciplines, the evaluation will result negative (insufficient, below 18/30) the student fails the exam and will have to repeat the whole exam on the next call.
The course aims to provide the students with information concerning the pharmacological and toxicological properties of the most important therapeutic classes of drugs. The main pharmacokinetic properties, the mechanism/s of action, therapeutic use, interaction/s with other drugs and adverse effects will be described for each group of drugs considered in the program. Particular emphasis will be given to the possible consequences of administering each of the therapeutic classes described during pregnancy and lactation. The aims also to provide the pharmacological and toxicological basis for a correct management and use of medicines in hospital
The course encompasses the following topics of Clinical Pharmacology:
Anti-inflammatory drugs: non steroideal anti-inflammatory drugs, corticosteroids
Neuropsychopharmacology: opioid analgesics, local and general anaesthetics, drugs used in the treatment of anxiety;
Drugs affecting the renal and cardiovascular function: diuretics, antihypertensive drugs, drugs used in treatment of pre-eclampsia and eclampsia;
Drugs acting on the blood: anticoagulants, antiplatelet drugs;
Antibiotic chemotherapics: general considerations on the mechanisms of action, resistance, general therapeutical strategies in the use of antimicrobial agents. The following classe will be described in detail: quinolones and fluoroquinolones, penicillins, cephalosporins, aminoglicosides, macrolides, antimicrobial agents inhibiting protein synthesis;
Drugs affecting the gastrointestinal function: prokinetic agents, antiemetics, agents used for diarrhea, constipation, agents used for the control of gastric acidity and treatment of peptic ulcers;
Drugs affecting uterine contractions: tocolytic and oxytocic
Farmacologia generale e clinica. Katzung B.G. Piccin Ed IX edizione italiana sulla XII edizione di lingua inglese
Farmacologia. Rang, Dale, Ritter, Flower, Henderson. Elsevier Ed. VII edizione italiana
The course consists of 20 hours of frontal lectures involving slides projection (prevalently written in Italian, but in cases of recent publication material, also in English). During classroom discussions, students are encouraged to interact with the lecturer with questions and curiosities. During lectures, lecturers will also present everyday cases and facts that can make it clear the application/importance of the subjects treated during the lessons. Students are required to attend the lessons as set out in the teaching regulations of the course and sign the attendance sheet to be able to take the exam. Lesson presentations will be available on accessible computerized platforms provided by the University (eg e-learning) to each student.
Presentations may provide links to web pages for further information. Student reception is obtainable on appointment via email.