Modulo I: Molecular and Instrumental approaches
To fully understand the topics addressed in the present course, students should possess basic notions of cellular biology
The course is designed to provide an updated overview of the molecular mechanisms underlying the maintenance of stemness and the role of microenvironment-niches, in the first module.
In the second module students will be introduced in the technologies of use in the research laboratories in molecular biology of health
Some topics selected from the syllabus will be assigned to the students who, in teams of 1-2 students each, will prepare an oral presentation that will be presented and discussed at the end of the course in front of the teacher and of their classmates. The topics that are the object of students' presentations are also part of the course program.
At the end of the course, students should be able to:
Understanding the concept of stem cells-microenvironment-niches
Identify suitable technologies in use
Know the different technologies of Imagin
At the end of the course, students should have developed the ability to effectively to research data in the scientific literature, to synthetize them in a PowerPoint and to competently discuss the presented material.
Definition of stem cells
Definition of microenvironment
Cell cycle Control
Apoptosis via intrinsic
Apoptosis Via Extrinsic
Embryonic stem cells
Adult stem Cells
Parenchymal stem Cells
Circulating stem cells
Proliferation-induced cells (IPS)
Transcription factors that induce proliferation
Transcription factors involved in differentiation
Some clinical applications of stem cells
Fluorecsenza
The FACS
Near-fast red fluorescence
Mass determination
The
Orbitrap
Mri
Piezoelectricity
Ultrasound
Pet
Image analysis
New preclinical applications of image analysis
Students will find the visual materials and articles relevant to the topics presented during the lectures on the Moodle platform, compatibly with the laws on copyright.
Highly recommended reading: Molecular Biology of the cell-5° edition- Alberts
Parent course
Borrowed from
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