HEMATOLOGIC DIAGNOSTIC TECHNIQUES
Fundamental skills in biological sample analysis and general laboratory techniques.
Assessment of learning will be conducted through a final exam, which will be held in an oral format.
The main objective of the course is to provide students with the fundamental knowledge of clinical hematology, with particular emphasis on laboratory techniques that allow for the diagnosis and prognosis of major hematological diseases.
Bone Marrow Hemopoiesis, Complete Blood Count, Assessment of Anemias and Leukopenias
Acute leukemias – morphological analysis of peripheral and bone marrow blood smears, main genetic and cytogenetic abnormalities, use of flow cytometry.
Lymphadenopathies and Lymphomas: laboratory techniques for diagnostic assessment and differential diagnosis; use of flow cytometry, immunohistochemistry, karyotype analysis, and molecular biology.
Plasma Cell Dyscrasias: laboratory techniques for diagnostic and prognostic assessment; serum protein electrophoresis, serum and urinary immunofixation; bone marrow analysis.
Hemostasis and Coagulation: the phases of hemostasis, pathophysiology; screening tests for the assessment of thrombocytopenia and coagulopathies; second-level examinations.
Thrombocytopenia and Thrombocytopathies: diagnostic assessment; laboratory tests in hemophilias and von Willebrand disease; laboratory tests in disseminated intravascular coagulation.
Thrombophilia: screening tests and assessment; thrombotic thrombocytopenic purpura; anticoagulant therapy and monitoring tests.
"The course will be conducted through lectures, supported by PowerPoint presentations featuring images and illustrative slides. Clinical case examples and reports of commonly used diagnostic tests for the assessment of hematological diseases will also be presented."