Fisiologia cardiovascolare

Degree course: 
Academic year when starting the degree: 
2022/2023
Year: 
1
Academic year in which the course will be held: 
2022/2023
Period: 
Annuity
Ore minime di frequenza: 
2
Standard lectures hours: 
2
Detail of lecture’s hours: 
Lesson (2 hours)
Requirements: 

Knowledge of vascular fluid dynamics and physiology of the cardiovascular system and skeletal muscle are required

No specific exam is foreseen at the end of the lesson

Assessment: 
Voto Finale

The course aims to offer students a quantitative view of the biomechanical aspects underlying the functioning of the myocardial muscle. In this way, the course intends to provide the necessary skills to understand in detail the complexity of its behavior in normal conditions and to make available to students the indispensable prerequisites for facing subsequent courses aimed at the study of pathological changes in the myocardium and their clinical treatment. surgical. Therefore teaching proves to be a fundamental cornerstone in the construction of the student's professional profile.
At the end of the course, the student will be able to:
1. describe the fundamental functional parameters that characterize the mechanical behavior of the myocardium;
2. explain how it works
3. use biophysical-quantitative tools (equations, graphs) to describe and analyze the physiological processes involved;
4. describe the correlations between structure, biophysical behavior and function
5. describe the mechanisms underlying the coordinated functioning of the myocardium and the vascular system
6. analyze the phenomena that lead to possible modifications of the quantitative and functional parameters as the organic conditions vary
7. discuss the topics addressed clearly and using the appropriate technical language.
8. explain how the changes in the functional balance found in physiological conditions lead to the onset of physiopathological conditions of clinical interest.
The teaching is preparatory to that of General Pathology; therefore the student is required to develop a knowledge of the physiological mechanisms introduced in this course in order to allow him an easy and profitable attendance of the next course.

During the lessons, all the aspects concerning the mechanical behavior of the myocardium during the cardiac cycle will be dealt with in detail.

Passive and active behavior of the myocardium: Frank-Starling's law for the heart and its functional significance. Atrial, ventricular and arterial pressures and changes in ventricular volume during the cardiac cycle. Pressure-volume diagram in the cardiac cycle. Mechanical work and cardiac performance and its modifications. Functional significance of the slope of the ventricular end systole phase. Guyton curves: balance between cardiac output and venous return

The teaching will be carried out through lectures conducted by the teacher with the aid of computer support materials. The student will be guided to the understanding of biomechanical processes through the presentation of images and general description schemes, accompanied by in-depth analyzes and explanations of biophysical-quantitative significance made using graphs, equations and numerical examples. Students will be invited to speak during the lesson for any questions, further explanations and / or insights.

Prof. Daniela Negrini can be contacted at the e-mail address: daniela.negrini@uninsubria.it.