ALLERGOLOGY AND CLINICAL IMMUNOLOGY
The lectures will address the following topics:
Innate functions and immune responses: focus on dendritic cells and natural killer cells. The complement system. Function of the main cytokines and chemokines in the immune response.
Cellular responses T and B. The characteristics of specific recognition.
Structure and functions of antibodies.
Helper T cells and helper subtypes. T helper 2 lymphocytes and allergy.
Hypersensitivity or 1st type immuno-pathogenic reactions or allergies. Pathogenetic mechanisms and IgE-mediated response. Hypersensitivity of 2nd-3rd-4th type. Characteristics of the immune cells involved and of the effector mechanisms.
Autoimmune diseases. Etiology, genetics and molecular mechanisms and examples of some therapies.
HIV infection and AIDS. Elements of transplant immunology.
Immunology for Health Degrees of Vera Del Gobbo (PICCIN, 4th edition, 2013).
Slide lessons: downloadable from the University E-learning website.
The course consists of 24 hours of lectures (2 CFU). These lessons will be supported by power point slides.
The teacher is available for in-depth or clarification meetings on the topics covered for individual students or groups of students. Student reception by appointment, to be agreed by e-mail (lorenzo.mortara@uninsubria.it), at the laboratory of Immunology and General Pathology (1st floor), Pavilion ex Colonia - Biomedical Pole, via Monte Generoso, 71 (int. 3), Varese.