ANATOMIC PATHOLOGY AND HISTOPATOLOGY

Degree course: 
Corso di Long single cycle degree (6 years) in MEDICINE AND SURGERY
Academic year when starting the degree: 
2019/2020
Year: 
5
Academic year in which the course will be held: 
2023/2024
Course type: 
Compulsory subjects, characteristic of the class
Credits: 
4
Period: 
First Semester
Standard lectures hours: 
48
Detail of lecture’s hours: 
Lesson (32 hours), Seminar (16 hours)
Requirements: 

-Knowledge of histology
-Knowledge of normal anatomy
-Knowledge of pathogenetic mechanisms of inflammatory and neoplastic processes

Exam

Assessment: 
Voto Finale

To know causes, pathogenetic mechanisms, tissue alterations (macroscopic, microscopic and molecular), natural history, and clinical evolution in relation to the treatment of the most frequent diseases.
To acquire the basis to collaborate with pathologist in the clinical management of patients through the learning of indications, advantages and limitations of various methods of analysis (cytological, histological and molecular) and the understanding of a cytological, histological, molecular and autopsy report

- Breast Pathology
- Female genital system pathology
- Nervous sytem pathology
- Head and neck pathology
- Bone and soft tissue pathology
- Skin Patology

Immune system
Diseases with autoimmune pathogenesis (SLE, systemic sclerosis, rheumatoid arthritis, Sjogren's syndrome, inflammatory myopathies). Immunodeficiency syndromes: congenital and acquired. Amyloidosis. Rejection of transplants

Head and neck pathology
Diseases of the oral cavity, nose and paranasal sinuses, salivary glands, pharynx and larynx. Salivary gland tumours. Tumours of the larynx, pharynx and nasal cavities.

Female genital system
Cervicitis; cervical polyps. Precancerous cervix. Cervical-uterine carcinoma. Endometrial hyperplasia. Benign tumours of the uterus. Malignant tumours of the uterine body. Morphological pictures of hormonal influences on the endometrium. Vesicular and choriocarcinoma. Endometritis, endometriosis and adenomyosis. Salpingitis. Vulvar dystrophies, preneoplastic lesions and tumours of the vulva. Ovarian tumours: primitive and metastatic.

Breast pathology
Hormones-driven morphological alterations in the breast. Mastitis and steatonecrosis. Benign tumours of the breast. Fibrocystic disease (fibrosis, cystic disease, adenosis, sclerosing adenosis, epithelial hyperplasia), fibroadenoma, phyllodes tumour, intraductal papilloma and papillomatosis, nipple adenoma. Breast carcinoma (in situ, ductal, lobular, medullary and other rare histotypes). Molecular profiles. Pathology of the male breast.

Central nervous system
Traumatic CNS lesions. Cerebral oedema and hypertension. Hydrocephalus. Cerebrovascular diseases. Viral encephalitis. Bacterial encephalitis and brain abscess. Prion diseases. Demyelinating diseases. Degenerative diseases (M. of Parkinson, M. of Alzheimer). Meningitis. Neurosyphilis. Pathology of the cerebral arteries. Gliomas. Meningiomas. Retinoblastoma, medulloblastoma. Schwannoma. Neurofibromas. CNS lymphomas. CNS metastases.

Soft tissues tumours
Immunohistochemical and cytogenetic diagnostics. Juvenile aponeurotic fibroma, nodular fasciitis, fibromatosis (palmar, plantar, penis, aponeurotic muscle - desmoid tumour) Dermatofibroma, dermatofibrosarcoma protuberans. Lipoma, lipoblastomatosis, liposarcoma. Leiomyoma, vascular leiomyoma, bizarre leiomyoma, leiomyosarcoma. Tumours of striated muscle tissue: rhabdomyoma, rhabdomyosarcoma. Haemangioma; intramuscular haemangioma; angiomatosis; hemangiopericytoma; glomangioma; pyogenic granuloma; hemangiosarcoma; Kaposi's sarcoma; malignant hemangiopericytoma. Alveolar sarcoma. Synovial sarcoma. Granular cell tumour. Clear cell sarcomas of tendons and aponeuroses. Epithelioid sarcoma. Myxomas. Desmoplastic small cell tumour.

Skin
Benign epithelial tumours (seborrheic keratosis, epidermal cysts, keratoacanthoma, tumours of cutaneous appendages) and malignant ones (actinic keratoses, basocellular epithelioma, squamocellular epithelioma). Dermal tumours: fibrous histiocytoma, dermatofibrosarcoma protuberans; Kaposi's haemangioma and sarcoma. Nevi and melanomas.

Osteoarticular Apparatus
Osteogenetic tumours: osteoma, osteoid osteoma, osteosarcoma. Chondrogenetic tumours: chondroma, chondroblastoma, chondrosarcoma. Ewing sarcoma / primitive neuroectodermal tumours (PNET), giant cell tumours, giant-cell tumour of tendon sheaths and villonodular tenosynovitis. Bone metastases

Lectures
Clinical cases

The teacher is available to students. Please contact at the following e-mail: stefano.larosa@uninsubria.it

Professors

Parent course