CHIMICA E PROPEDEUTICA BIOCHIMICA
No prerequisites are needed
Chemistry and biochemistry
Knowing the biochemical basis of biological phenomena, mostly those important in physiology, diseases, and clinical practice, at the level of cells, tissues and total body. Approaching the own language and method of experimental life sciences.
BIOLOGIA, Docente Giovanni Porta
The molecular, cellular, tissue and systemic scale of the human physio-pathology explained by the the biological and genetic point of view. Introduce the dictionary of the experimental and biological science applied to medicine. The knowledge of the pathological phenotype as the interaction of the genotype with the environment.
Chemistry and biochemistry
1) Solutions: water properties, solvation and electrolytes, hydrogen bond, concentration of the solutions.
2) Acid base balance: fundamentals (strength of the acids and the bases pH, pK), buffering, biological buffers, Handerson-Hasselbalch equation
3) Organic compounds. Functional groups: alcohol, aldehydes, ketones, carboxyl acids, amines. Nomenclature and main characteristics. Main types of isomers. Aromatic compounds.
4) Aminoacids and protein structure; Collagen, Myoglobin and hemoglobin, cooperativity and allosteric interactions.
5) Reaction kinetics: enzymes and enzymatic kinetics
6) Bioenergetics: principles of the thermodynamics, free energy and spontaneous reactions, high energy bonds, redox potentials, redox pairs of particular biological importance.
7) Oxidative phosphorylation, Tricarboxylic acid cycle, aerobiosis and anaerobiosis, glycolytic pathway (basic).
BIOLOGIA
Mendelism
The function of DNA
The structure of DNA
Duplication of DNA
Semi-conservative duplication
Replication fork
RNA
Transcription
Traduction
Proteic Syntesis
Genetic code
Bacteric ricombination
Chromosomes
The mitosis
The meiosis
Mutations
Examples of mutations
Molecular biology
Chemistry and biochemistry
All didactic material presented in the classes as well the one necessary for the preparation of the examination (slides, pantries, exercises) is available in the e-learning platform.
Textbook suggested according to the individual preferences (written in Italian).
M. Samaja, R. Paroni - Chimica e Biochimica per le lauree triennali dell’area biomedica – Piccin editore (simple but complete, suitable for the Biochemistry class too).
Fiecchi A., Galli Kienle M., Scala A, Chimica e propedeutica biochimica - edi ermes editore (synthetic and complete);
Stefani S., Taddei N. - Chimica, Biochimica e Biologia applicata - Zanichelli editore (more details and points of view);
Biology
Text provided in the e learning platform
text: Tiepolo Laudani , Le basi biologiche dell'Ereditarietà ed La Goliardica Pavese.
All the slides and the exercises shown in classes is available in the e learning platform