APPLIED ORGANIC CHEMISTRY
- Overview
- Assessment methods
- Learning objectives
- Contents
- Full programme
- Bibliography
- Teaching methods
The contents of the courses of Organic Chemistry 1 and Organic Chemistry 2 are prerequisites
The verification of the knowledge acquired by the student will be carried out through the evaluation of reports in which the experiences and results obtained will be illustrated. Furthermore, the presentations of papers related to the experiences performed in the laboratory will be evaluated.
The final grade, of course, will also depend on the commitment shown by the student in conducting experiments in the laboratory.
The main objectives of the course are
• to provide an overview of the main techniques used in an organic chemistry laboratory by performing mini sequences of reactions
• to introduce students to bibliographic research
At the end of the course students will have become familiar with the procedures that are most commonly used in an organic chemistry lab and will have acquired the tools to conduct and design simple organic syntheses.
Students will be required to perform some synthetic sequences, using even complex experimental procedures, such as those in inert atmosphere. The products of the single reactions will be isolated and characterized by 1H NMR and IR spectroscopy.
Furthermore, the student will be introduced to the bibliographic research and the articles relating to the experiences carried out in the laboratory will be discussed and commented on.
Enantioselective reduction of acetophenone with CBS reagents.
Chemoselective reduction of mono-methyl azelate
Synthesis of a beta-lactam and its enzimatic resolution
Synthesis of a diaryliodonium salt and its use in an indole arylation reaction
Wittig synthesis of the trans-stilbene
Synthesis in three steps of the 3,4-diidro-3-(4-methylphenyl)-2H-1,3-benzossazine
Final test: synthesis of a bis-4-hydroxycoumarin by reaction of coumarin and an unknown aldehyde.
Papers related to the experiences performed in the laboratory.
Frontal lessons related to the explanation of the experiences to be conducted in the laboratory. Laboratory assistance during the execution of experiments.