BIOCHEMISTRY 1
Biomolecules characteristics; Proteins: modifications, allostery; enzymes and their activity controls; Biological Membranes and Transport; The Composition and Architecture of Membranes. Membrane Dynamics. Solute Transport across Membrane. Glucose transport and its regulation. Molecules that can pass the BBB. Haemoglobin and myoglobin. Biosignaling: general features of signal transduction. Bioenergetics and Biochemical Reaction Types. Vitamins and essential molecules. Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway. The Metabolism of Glycogen. The Citric Acid Cycle. Digestion, Mobilization, and Transport of lipids. lipoproteins; metabolism of cholesterol ; scavenger receptors; atherosclerotic process. Amino Acid Oxidation and the Production of Urea Metabolic Fates of Amino Groups. Principles of Metabolic Regulation. Analysis of Metabolic Control: insulin and glucagon; AMPK. Synthesis and catabolism of HEME.
Introduzione alla biochimica. Lehninger, Nelson, Cox. Zanichelli
Le basi della Biochimica Champe PC, Harvey RA, Ferrier DR Zanichelli
Chimica e biochimica per le lauree triennali dell'area biomedica Michele Samaja - Paroni Rita -PICCIN
Biochimica e Biologia 2/ed - per le professioni sanitarie. Di: Rita Roberti, Giovanni Alunni Bistocchi, Cinzia Antognelli e Vincenzo Nicola Talesa - McGraw-Hill
The course will be organized in 36 hours of lectures with presentation of slides (tendentially in Italian but, in cases of recently published material, also in English). During the explanation in the classroom the students are invited to interact with the teacher with questions and curiosities. During the lessons, the teacher will also present cases and daily facts that can help understand the application / importance of the subjects taught. Students are required to attend classes as established in the academic regulations of the course of study and to sign the attendance sheet in order to take the exam. The teacher undertakes to make available the presentations projected in lectures and other material of interest (scientific articles) through the University computer platforms (i.e. e-learning) to which the students have access.
The teacher's presentations may contain links to web pages for further information. To receive students, make an appointment by email with the teacher.