PHARMACOLOGY MODULE
- Pharmacokinetic Exercises. the main routes of drug administration, and the pharmacokinetic processes of absorption, distribution, metabolism and elimination of drugs in healthy subjects, in patients, during pregnancy and in puerperium. Quantitative pharmacokinetic topics will also be used to set a correct dose, such as distribution volume, clearance, half life, maintenance dose, and loading dose. The concept of bioavailability and the equivalent drug will be addressed.
- Pharmacodynamic properties: the main mechanisms underlying drug action. They will also discuss the theoretical basis for the interpretation of drug action by imparting the concepts of agonist, antagonist, partial agonist. Dosage-response curves that allow you to interpret efficacy and pharmacological potency. Drug-toxicology topics will be addressed to interpret toxic drug effects, drug interactions, abuse, tolerance, addiction.
-Examples of pharmaceutical legislation, experimentation. The main laws in force in Italy and the European Union concerning the production, classification of medicines, prescription and pharmacovigilance. Preclinical and clinical studies will also be described for the discovery of new drugs.