CHIMICA E PROPEDEUTICA BIOCHIMICA
None in particular, do not forget the arithmetic of the primary school, especially equivalents and proportions.
Knowing the chemical basis of biological phenomena, mostly those important in physiology, diseases, and clinical practice, at the level of cells, tissues and total body. Approaching the own language and method of experimental life sciences.
1) CHEMICAL BONDS. Covalent and ionic bonding, molecules and crystals
2) SOLUTIONS. Water properties, solvation and electrolytes, hydrogen bond, concentration of the solutions.
3) ACID-BASE BALANCE. Fundamentals (strength of the acids and the bases pH, pK), buffering, biological buffers, Handerson-Hasselbalch equation
4) BIOENERGETICS (I). Principles of the thermodynamics, free energy and spontaneous reactions, high-energy bonds.
5) BIOENERGETICS (II). Redox potentials, redox pairs of particular biological importance, oxidative phosphorylation.
6) ENZYMES. Reaction rate and chemical equilibrium, catalysts and biological catalysis, specificity and control of enzymatic reactions
7) ORGANIC COMPOUNDS. Functional groups: alcohol, aldehydes, ketones, carboxyl acids, amines. Nomenclature and main characteristics. Main types of isomers. Aromatic compounds.
8) LIPIDS. Fatty acids, triglycerides and phospholipids. Detergents and micelles. NUCLEIC ACIDS. Nitrogenous bases and nucleotides, DNA and RNA
9) CARBOHYDRATES. Monosaccharides, pentoses, hexoses, anomers and epimers; glycosidic bond, di- and polysaccharides
10) AMINOACIDS AND PROTEINS. General structure and properties of the main side chains. Peptide bond and protein structure.
All didactic material presented in the classes as well the one necessary for the preparation of the examination (slides, pantries, exercises) is available in the e-learning platform.
Textbook suggested according to the individual preferences (written in Italian).
M. Samaja, R. Paroni - Chimica e Biochimica per le lauree triennali dell’area biomedica – Piccin editore (simple but complete, suitable for the Biochemistry class too).
Fiecchi A., Galli Kienle M., Scala A, Chimica e propedeutica biochimica - edi ermes editore (synthetic and complete);
Stefani S., Taddei N. - Chimica, Biochimica e Biologia applicata - Zanichelli editore (more details and points of view);
Roberti R., Alunni Bistocchi G., Elementi di Chimica e Biochimica - McGraw Hill editore (very simple and synthetic).