CHEMOTHERAPY
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- Assessment methods
- Learning objectives
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main notions of anatomy, biochemistry, pathology and physiology and all the other proponed by the degree program
Oral examination
At the end of the course the student will be able to evaluates and describes, on the basis of the knowledges of pharmacodynamic and pharmacokinetic characteristics, the properties of a drug and to be able to individuate the therapeutic strategies considering the chemical structure and the target of the drug, in addition the knowledge about the pharmacokinetic properties will be used to be able to consider the therapeutic and toxicologic effects
deepen the basic notions and mechanism of the main classes of antimicrobial antibiotics: - Beta-lactams, other antibiotics active on the bacterial wall, - Aminoglycosides, tetracyclines, macrolides, chloramphenicol, other antibiotics active on synthesis protein
- Sulfonamides, trimethoprim, other antimetabolites. Quinolones, other antibiotics active on the bacterial DNA / RNA.
Notions on:
- Antibacterial antibiotics - antiviral drugs - notes on antiprotozoal and anthelmintic drugs.
The mechanisms and methods of action and effectiveness of:
- Cytotoxic anticancer drugs.
- Monoclonal antibodies. Modifiers of biological response.
- Hormonal treatment of neoplasms.
Chemotherapy
1. Beta-lactams, other antibiotics active on the bacterial wall.
2. Aminoglycosides, tetracyclines, macrolides, chloramphenicol, other antibiotics active on protein synthesis.
3. Sulfonamides, trimethoprim, other antimetabolites. Quinolones, other antibiotics active on the bacterial DNA / RNA.
4. Anti-mycobacterial antibiotics - antiviral drugs - notes on antiprotozoal and anthelmintic drugs
5. Cytotoxic anticancer drugs.
6. Monoclonal antibodies. Modifiers of biological response.
7. Hormonal treatment of neoplasms.
- Rossi F, Cuomo V, Riccardi C Farmacologia – Principi di base e applicazioni terapeutiche, Edizioni Minerva Medica, Torino
- Rang HP, Dale MM, Ritter JM Farmacologia, Casa Editrice Ambrosiana, Milano
- Golan DE et al. Principi di Farmacologia – Le basi fisiopatologiche delle malattie, Casa Editrice Ambrosiana, Milano
- Katzung BG Farmacologia generale e clinica Piccin, Padova
- Howland MD, Mycek MJ Le basi della farmacologia, Zanichelli, Bologna
- Birkett DJ Elementi di farmacocinetica, Piccin, Padova
Frontal lessons
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