CLINICAL PHARMACOLOGY
A thorough comprehension of the course entails basic knowledge in general pharmacology (imparted during the first year of the Midwifery bachelor degree in the Course of Biomedical Sciences), human physiology (imparted during the first year of the Midwifery bachelor degree in the Course of Genetica Medica e Fisiologia Umana) and general and clinical pathology (imparted during the first year of the Midwifery bachelor degree in the Course of Microbiology, General and Clinical Pathology).
There are no constraining pre-requisites for this course.
The course aims to provide the students with information concerning the pharmacological and toxicological properties of the most important therapeutic classes of drugs. The main pharmacokinetic properties, the mechanism/s of action, therapeutic use, interaction/s with other drugs and adverse effects will be described for each group of drugs considered in the program. Particular emphasis will be given to the possible consequences of administering each of the therapeutic classes described during pregnancy and lactation. The aims also to provide the pharmacological and toxicological basis for a correct management and use of medicines in hospital
The course encompasses the following topics of Clinical Pharmacology:
Anti-inflammatory drugs: non steroideal anti-inflammatory drugs, corticosteroids
Neuropsychopharmacology: opioid analgesics, local and general anaesthetics, drugs used in the treatment of anxiety;
Drugs affecting the renal and cardiovascular function: diuretics, antihypertensive drugs, drugs used in treatment of pre-eclampsia and eclampsia;
Drugs acting on the blood: anticoagulants, antiplatelet drugs;
Antibiotic chemotherapics: general considerations on the mechanisms of action, resistance, general therapeutical strategies in the use of antimicrobial agents. The following classe will be described in detail: quinolones and fluoroquinolones, penicillins, cephalosporins, aminoglicosides, macrolides, antimicrobial agents inhibiting protein synthesis;
Drugs affecting the gastrointestinal function: prokinetic agents, antiemetics, agents used for diarrhea, constipation, agents used for the control of gastric acidity and treatment of peptic ulcers;
Drugs affecting uterine contractions: tocolytic and oxytocic
Farmacologia generale e clinica. Katzung B.G. Piccin Ed IX edizione italiana sulla XII edizione di lingua inglese
Farmacologia. Rang, Dale, Ritter, Flower, Henderson. Elsevier Ed. VII edizione italiana