PHYSIOPATHOLOGY OF THE CNS
- Overview
- Assessment methods
- Learning objectives
- Contents
- Bibliography
- Teaching methods
- Contacts/Info
Good knowledge of physiology and Neurophysiology in particulat
final oral exam where the students must demonstrate that (1) they are capable of explaining the pathogenesis of a chosen neuropathological condition and the related functional derangements; and (2) that they posses a general knowledge of the topics dealt with in the course
-- Understanding the functional organization of the Central Nervous system
-- Understanding how the molecular and cellular processes in neurons and glia and the organization of neural circuits give rise to sensory information processing, motor control, sleep, memory, learning, emotions, language, thought and motivated behaviour
-- Understanding how genetic, environmental factors and psychological experience may interact in generating neurological and psychic disturbances
-- Knowing the main features of the most important CNS pathologies (Parkinson's, Huntington's, Alzheimer's diseases, epilepsy and migraine, ALS, Schizophrenia, Bipolar Spectrum Disorders, Autistic Spectrum Disorders, ADHD)
-- Identify the main paths and approaches for research in Neuroscience and understand the specificities of diagnostic, monitoring, symptomatic and disease-modifying strategies and approaches
-- Capacity to identify how a genetic alteration, an environmental factor or the impairment of a cellular function may interfere with the normal functioning of cerebral circuits and give rise to neurological or psychic derangement
-- Capacity to illustrate the specific features of Central Nervous System pathophysiology, of the neuron-glia interaction, of the processes of neurodegeneration and of possible strategies of neuroprotection
-- Capacity to describe and explain the modalities of onset of a neuropathological picture
NeuroPhysiology (18 h)
 	Functional organization of the Central Nervous System (CNS)
 	Synaptology
 	Neurotransmitters in the CNS
 	Neuromodulation and neural computing
 	Neuronal and synaptic plasticity
 	Neuronal development and degeneration. Glia and neurons
 	The organization of the cerebral cortex
 	Sensory system and central processing of sensory information
 	Motor control
Sensory and motor disturbances (12 h)
 	Multiple Sclerosis (MS)
 	Cerebellum physiopathology
 	Basal nuclei physiopathology
 	Amyotrophic Lateral Sclerosis (ALS)
 	Parkinson's Disease (PD)
 	Huntington's Disease (HD)
Physiopathology of memory and learning (4 h)
 	Alzheimer's Disease (AD)
The limbic system - Mood disturbances: Anxiety and Depression (BDS) (4 h)
Epilepsy and Migraine (2 h)
The neural basis of consciousness -- cognitive disturbances (8 h)
 	Autistic Spectrum Disorders (ASD) and Attention Deficit + Hyperactivity Disorder (ADHD)
 	Thought disturbances - Psychosis and Schizophrenia
 	The organization of higher functions - Language
-- Principles of Neural Science E.R. Kandel, J.H. Schwartz, T.M. Jessel - McGraw Hill Professional, 2013
-- Fundamental Neuroscience, L.R. Squire, D. Berg, F.E. Bloom et al. - ELSEVIER, 4th ed., 2012
Lectures
In addition to the slides, Relevant scientific articles can be accessed at the link of the University at Busto (ask the teacher for access)
Professors
Borrowers
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  Degree course in: BIOMEDICAL SCIENCES
