1. Normal microbiota
2. Corinebacteria: generality; C. diphteriae and other corinebacteria.
3. Streptococci: Generality, classification. Toxins and enzymes produced.Disorders. Laboratory diagnosis.
4. Staphylococci: generalities and classification. Toxins and enzymes. Drug resistance. Surface antigens. Disorders. Laboratory diagnosis.
6. Neisserie: generalities and classification. Antigens and adhesion structures. Pathogenesis. Epidemic meningitis and gonorrhea.
7. Gastrointestinal bacteria of medical importance:
Enterobacteria: general features, antigenic structure, classification. Salmonella and Shigella infections. E. coli.
Vibrions: generality and taxonomic classification of Vibrio cholerae. Pathogenesis of cholera and mechanism of action of cholera toxin.
The genus Campylobacter: physiology and general characteristics. Epidemiology, pathogenesis, caused pathological forms
Helicobacter pylori: physiology and general characteristics.
8. Brucelle: Generalities and classification. Pathogenesis. Epidemiology and prevention.
9. Bordetella and Haemophilus: Generalities. Exotoxins of Bordetella pertussis. Antigenic structure. Vaccination. Pathological forms caused by Haemophilus influenzae.
10. Spore-forming aerobic bacilli: The genus Bacillus. B. anthracis. B. cereus.
11. Spore-forming anaerobic bacilli: the genus Clostridium. Main species and classification. Mechanism of action of tetanus and botulinum toxins. Pathogenesis of tetanus, botulism, gas gangrene.
12. Mycobacteria and tuberculosis infection: General properties, cultivation and classification. Immunity to Mycobacterium tuberculosis. Pathogenesis of tuberculosis infection. Diagnosis, epidemiology, prevention, chemotherapy treatment.
M. leprae and non-tuberculous mycobacteria (also called atypical).
13. Obligatory intracellular parasites: rickettsias and chlamydiae.
15. Mycoplasmas: Generalities. Pulmonary and genitourinary tract infection.
16. Superficial mycoses and systemic mycoses.
18. Picornavirus: General characteristics. Pathogenesis of poliomyelitis and Coxsackie virus infections. Polio vaccines: attenuated and inactivated vaccines.
18. Influenza viruses: generalities, genome structure, antigens and antigenic variability. Pathogenesis and complications of infection. Transmission routes; vaccination prevention and control. Laboratory diagnosis.
19. Paramyxovirus: generalities. Mumps virus, measles virus, respiratory syncytial virus 20. Rabic virus: general characteristics, antigens and host spectrum
22. Rubella virus (Togavirus): Generality. Pathogenesis of infection Transmission to the fetus. Congenital infection
23. Rotavirus and other viral gastroenteritis agents
25. Herpes viruses: General properties, genome organization, replication. Classification. Persistence of the viral genome and reactivation. Pathological forms caused by different herpes viruses.
26. Poxvirus: outline of the smallpox virus and its eradication
27. Hepatitis viruses: generalities, classification and pathologies produced. Chronic forms of hepatitis and risk of liver tumors. Serological and molecular diagnosis of viral hepatitis.
28. Oncogenic DNA viruses: Papillomavirus: condylomas and papillomas. Tumors induced by herpes viruses
29. Retrovirus: Structure and organization of the genome. Antigens and replication cycle. Reverse transcriptase. Genetic classification and variability. HIV and cell tropism. Pathogenesis of acquired immunodeficiency syndrome (AIDS). Epidemiology and transmission pathways. Serological and molecular diagnostics.