GYNAECOLOGY AND OBSTETRICS
ALLERGOLOGY AND CLINICAL IMMUNOLOGY
No pre-requisites for this course are required.
ALLERGOLOGY AND CLINICAL IMMUNOLOGY
The course provides the principles of allergology and clinical immunology, in particular of innate and acquired immunity, their dynamics and their functioning in health and illness.
The student will have to demonstrate:
1) Have learned about the functioning of the various cell types, their interactions and the basic molecules of the immune system;
2) Have developed understanding and description skills of the various mechanisms of the allergy and the various types of hypersensitivity as well as immune system modulation processes in vaccines and immunotherapy;
3) to be able, through a critical and concise discussion of the topic of interest, to deepen such knowledge autonomously in the application aspects of that science;
4) to know how to conceive and support theoretical and practical arguments in order to solve specific problems of allergology and immunology.
ALLERGOLOGY AND CLINICAL IMMUNOLOGY
The front lessons will address the following topics:
General characteristics of the immune system. Internal innate defenses. Molecules and cells of innate immunity. Acute inflammatory reaction, proinflammatory cytokines and acute phase proteins (4h).
Antigen recognition by T lymphocytes and lymphocytes B. Formation of antigen receptors on lymphocytes. Presentation of the antigen to lymphocytes T. The Higher Complexity of Istocompatibility and its functions (4h).
Lymphocyte activation mechanisms. Positive and negative selection in thymus. The response of T cells (4h).
The humoral immune response. Various types and functions of antibodies. Dynamics of acquired immunity. Immune memory (4h).
Allergies and allergic diseases. The genetic and environmental bases of the allergy. Hypersensitivity (4h).
Deficiencies of host defense mechanisms. Immune deficiency diseases and HIV. Autoimmunity. Transplantation. Immune surveillance of tumors. Various types of vaccines (4h).
ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Janeway Immunobiology (PICCIN, 8th Edition, 2014).
Slide lessons: downloadable from the University's E-learning site.