Physiology
The course will require mathematical, physical, chemistry basis. Knowledge of Animal Biology and Cell biology is also required.
The examination is oral about all parts of the course. The final score is given in 30ies: the examination is successful if a score ≥ 18/30
SUBJECT GOALS
Introduction
The course will provide the physiological basis for understanding the lives of animals at every level of organization: molecular, cellular, whole organism.
Training goals
The learning aim will be
-Acquisition of the knowledge of physiological process at the different levels, from the molecular to the whole organism
Understanding the structure function relationships and the origin of the physiological functional response
The use of the correct scientific and physiological language
Understanding the importance of different aspect of physiology in different disciplines as biotechnology, bio-medical science or environmental science
The capability of interpretation of functional graphical physiological plot
The ability to understand and explain the animal function by graphical representation, simulation or by multimedia approach.
LEARNING OUTCOMES
Knowledge and understanding (Knowledge and know)
Acquisition of mindful independent knowledge and of the correct scientific and physiological language that shows the study on advanced textbooks and multimedia tools (video, simulations etc.) and knowledge of some cutting-edge issues in the specific field of study
Applying knowledge and understanding (Skills and know how)
Understanding the importance of different aspect of physiology in different disciplines as biotechnology, bio-medical science or environmental science. The capability of interpretation of functional graphical physiological plot.
The ability to understand and explain the animal function by graphical representation, simulation or by multimedia approach.
Introduction- Homeostasis Feedback (negative and positive) internal and external environment- permeability and membrane transports
Membranes structure and regulation, compositions, membrane protein, membrane organization. Diffusion, membrane flux, active transport and facilitated diffusion, epithelia transport. Electric property of the membrane, Nerst and Goldman Equation, Donnan Equilibrium, Resting and action potential, Voltage clamp, ion channels Patch clamp and single channel recordings.
Signal transduction, Signal propagation Synapse, Synaptic Receptor and channel, Synaptic plasticity, LTP and LTD
Messenger and regulatory protein, Membrane signal transduction,
Muscle and Movements, Sarcomere structure, sliding filament theory, regulation of contraction, Role of Calcium, Mechanisms of muscle contraction, Cardiac muscle and smooth muscle.
Nervous systems evolution, Central nervous systems and central control, the autonomic nervous system.
Homeostasis, Endocrine System, physiological effect of hormones, Control of Nutrition, water and saline balance, metabolic and developmental hormones, reproductive hormones, Circadian rhythms and biological clocks
Circulation and the heart, general plan of the circulatory system, Mechanical property of the heart, Electric activity and coronary circulation, Hemodynamics, the peripheral circulation, the lymphatic system, capillary, control of the central cardiovascular system
Gas Exchange, oxide ad carbon dioxide in the blood, respiratory pigments, lung in vertebrates, and cardiovascular or nervous control of respiration.
Ionic and osmotic balance, balance of water and salt, osmoregulation organs, vertebrate kidney, Henle loop, excretion of nitrogenous wastes.
Feeding digestion adsorption, alimentary system, nutrients, alimentary canal, motility, structure, gastrointestinal secretion, absorption.
Metabolism and temperature relations, energy of locomotion and environmental influence.
“Fisiologia” E. D’Angelo & A Peres, Edi-Ermes Milano 2011
Didactic material, slide and video in e-elarning site
"Fisiologia umana"
Un approccio integrato • 7/Ed. • Con Mastering A&P
Dee Unglaub Silverthorn- Pearson 2017
"Human Physiology: An Integrated Approach, 7th Edition
Dee Unglaub Silverthorn, University of Texas, Austin Pearson
Fisiologia e Biofisica delle cellule V. Taglietti - C. Casella Edises
Frontal lectures72 hors, Lectures will be support by slide and video presentation
Professors
Borrowers
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Degree course in: BIOTECHNOLOGY